Fulcrum 5's are a good solid wheelset, and 1000km are still practically new....so would hold no issue. I know multiple people with fulcrum 5's, and train and race on them....and have found them to be a good wheelset.
In regards to…"
My 2 cents worth. Given you are looking for a road bike, and have a $10k budget, I'll assume you want to race (there are different spec road bikes for race as opposed to just road riding with mates).
I'll also assume you want a…"